Over the 11-year timeframe, the annual exposure rate per 100,000 population doubled. For instance, a case study reported in 2013 in the Journal of Substance Usedocumented a possible case of promethazine abuse leading to physical dependence, with the withdrawal symptoms being more psychological or emotional in nature. Both should be tapered if you would like to stop taking them, to. More on promethazine use and addiction characteristics here Promethazine, a phenothiazine, is associated with a possible risk for QT prolongation. Doses higher than that make me struggle to keep my head up, and walking is rather difficult. Phenergan should not be given to patients with a known hypersensitivity to promethazine or to any of the excipients. Lean — also known as purple drank, purple lean, sizzurp, dirty sprite, and lean drink—is a made of combination of prescription-strength cough medicine, soft drinks, and hard, fruit-flavored candy. This combination medication is used to treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (e.g., sinusitis, bronchitis). Ondansetron is an anti-nausea phenergan dependency medication used to prevent nausea and vomiting caused by cancer chemotherapy.It is also used to prevent vomiting and nausea after surgery. There also are a few references in the literature to cases of promethazine abuse alone. Chemical dependency is a common, chronic disease that affects up to 25 percent of patients seen in primary care practices. Doses higher than that make me struggle to keep my head up, and walking is rather difficult. Phenergan is not addicting. It may also be used for sedating people who are agitated or anxious. Phenergan should not be used in patients in coma or suffering from CNS depression of any cause. There also are a few references in the literature to cases of promethazine abuse alone. Both should be tapered if you would like to stop taking them, to. Learn what to expect from withdrawal if you become dependent on or addicted to codeine Medications Recovering Addicts Should Avoid After Rehab. Exposures were most prevalent. Medications consisting of both codeine and promethazine are Schedule V, meaning they have a lower potential for abuse, but there is still abuse potential and so they are controlled substances. I don't usually go to the hosptial until I have exhausted all my home RX's and the usually methods of dark room, sleep, quiet. I take Lunesta, which hardly works, but when I add Phenergan 25mg it does the trick. Chemotherapy drugs increase secretion of serotonin, which stimulates serotonin (5-HT3) receptors in the brain, causing nausea and vomiting. It may also be used for sedating people who are agitated or anxious. I have received phenergan a lot with my migraines. I take Lunesta, which hardly works, but when I add Phenergan 25mg it does the trick. It is a pain reliever and a cough suppressant. When used for surgery, promethazine is usually taken the night before the surgery. Results: There were 354 single product abuse or misuse exposures—95 PA and 259 PC. For motion sickness, promethazine is usually started within 1 hour before traveling. (844) 505-4799 Article Contents. Phenergan is available as a generic drug.Common side effects of Phenergan (promethazine HCI) include. It's more likely to make you feel sleepy than other antihistamines This is what Webmd.com says about how to use Phenergan: Take this medication by mouth with or without food, usually 4 times daily as needed or as directed by your doctor. Uses.